Tag Archives: Asthma

Asthma – Condition Resources

Important to know: Chronic health conditions should be addressed under direct medical supervision of your GP or consultant, and acupuncture would be an adjunct or complement to usual care – we advise that you let you doctor know when you use this approach.

Asthma affects around 5.4 million people in the UK. The British Acupuncture Council has produced a research based fact sheet for patients, as well as a review of the evidence for effectiveness in this area (see Resources, below).

Research and Resources on Asthma and Acupuncture:

A scholarly search of the available research studies on “acupuncture and asthma” reveals over 44,000 papers from journals, and narrowing this to “systematic review” leads to over 15,000 hits, of which 38% have been carried out since 2017.  From this we can deduce that acupuncture is being used extensively, traditionally and currently in this area; widely scientifically researched in this area, and that the pace at which the research is being carried is increasing – leading us to understand this is an area worthy of scientific appraisal and consideration.  

Interpreting the Evidence:

Any research articles referred to on this page (and on the BAcC helpsheets) are listed in full in the References section at the foot of the relevant page.  Within the text, where studies are quoted as sources of the information being given, the first author’s name and the year of the paper is used (as authors usually have numerous publications), with the full title, journal, etc listed in the References section, in alphabetical order by Author surname to enable identifying and finding the original source paper.

When reading health research, it is important to know that Systematic Reviews or Meta Analyses of a large number of high-quality research studies are the very best way to be able to say to what extent a given treatment can address a condition, symptom, or set of symptoms.  The next best level of evidence is the individual Randomised Controlled Study (RCT) which uses a systematic technique to compare two or more groups of patients receiving different treatments (or a treatment against a “control”, or no treatment).  In acupuncture trials, the nature of the control group is of particular interest as it is hard to blind a patient to whether they are having a needle inserted or not, and even more challenging to blind the researcher/team to this.

The means and quality of how research is carried out varies considerably from country to country, and in terms of how an intervention is compared to another intervention (or a control).  Of note is the fact that “sham” acupuncture (where needles are placed in apparently inert locations rather than traditional acupuncture points) is not really an inert process as it has physiological effects, so that comparing sham and “true acupuncture” may therefore not give a clear picture alone; but and form a part of a research body where acupuncture versus no treatment, vs conventional treatment or vs a different approach/modality also form part of the evidence base.

The n= figure (where quoted in research) tells you how many people were participants in the study, and usually the larger a study (when it is of good quality and design), the more likely it is to be reliable and applicable to larger populations. When (statistical) “significance” is discussed in view of studies it has a very particular meaning – it is the confidence in the data (using statistical tests) that tells us how likely a result could have just come about by chance. The lower the possibility of a chance result, the more likely it is due to the intervention in the experiment. When you are reading a trial/study, the “p” is the number telling us of significance, and this must be under 5% (or p less than 0.05) to mean we can say it is a (statistically) “significant” result.

The Research

Asthma:

There is some evidence from trials to suggest acupuncture may be a useful adjunct to usual care, be beneficial over placebo and can improve quality of life and be cost effective in asthma (Karlson & Bennicke, 2013; Chu et al 2007; Rheinhold et al, 2014).

Some systematic reviews have been carried out into acupuncture in this area, with the most recent looking at 11 trials, found that many were only small trials and that more research would be needed (Martin et al, 2002) and a Cochrane meta-analysis a year later (McCarney et al, 2003) looked at 12 studies (n=350) drew a similar conclusion. More recently Chen et al, (2020) proposed a protocol for a new systematic review and meta analysis of the research, as they noted that an increasing amount of research trials have been done in this area in recent years, warranting a further, large and structured review.

Allergic Asthma:

Brinkahus et al, (2017) carried out a large randomised pragmatic trial in Germany (n=1445) giving acupunctrure in addition to usual care for allergic asthma, and comparing to a usual care alone group.  They found symptomatic improvement, as well as improvement in quality of life (asthma quality of life questionnaire – AQLQ) measures for the acupuncture group.

Mechanisms of action:

In the condition of allergic asthma, inflammatory considerations may play a key part in the process. Acupuncture has been shown to have anti-inflammatory effects, and a review article (Kavoussi & Ross, 2007) suggests this may be due to activation of the vagus nerve, alongside deactivation of inflammatory macrophages and other proinflammatory cytokines which have been seen in studies.

Other studies (Zijlstra et al, 2003) suggest some of the anti-inflammatory effects exhibited in acupuncture may be due to stimulation of vasodilators, neurotransmitters and painkillers (beta-endorphins, CGRP and substance P) within the body when acupuncture is applied, and these further stimulate cytokines and nitric oxide, all of which play roles in inflammatory states. 

Regarding Your Individual Condition and Symptoms:

Whilst the scientific studies are of great interest to researchers and acupuncturists in terms of comparing protocols, for the patient not versed in research they are less accessible, which is why when we asked “can acupuncture work for my (condition or symptom) we are not able to give a simple yes or no response.  We are able to tell you what experience we have had in our decades of experience in practise, of the types of outcomes we have seen in similar cases, and give you an idea of our level of experience and knowledge in that area, and how this could relate to your own individual situation.  For this, we recommend booking a free telephone consultation where we can answer any questions you have and give a realistic appraisal of what acupuncture may be able to provide.

Resources:

British Acupuncture Council evidence based factsheet about asthma including specific research, trials and mechanisms of action for acupuncture in this condition.

British Acupuncture Council Review Paper: Bronchial asthma and acupuncture: the evidence for effectiveness

References:

Brinkhaus, B., Roll, S., Jena, S., Icke, K., Adam, D., Binting, S., Lotz, F., Willich, S.N. and Witt, C.M., 2017. Acupuncture in patients with allergic asthma: a randomized pragmatic trial. The Journal of Alternative and Complementary Medicine23(4), pp.268-277.

Chen, Y.M., Xie, X.L., Xiao, P.Y., Wang, Q.H., Wang, J.S., Yu, X.D. and Deng, S., 2020. Acupuncture on treating asthma: A protocol for systematic review and meta analysis. Medicine99(1).

Chu, K.A., Wu, Y.C., Ting, Y.M., Wang, H.C. and Lu, J.Y., 2007. Acupuncture therapy results in immediate bronchodilating effect in asthma patients. Journal of the Chinese Medical Association70(7), pp.265-268.

Karlson, G. and Bennicke, P., 2013. Acupuncture in asthmatic children: a prospective, randomized, controlled clinical trial of efficacy. Alternative therapies in health and medicine19(4), p.13.

Martin, J., Donaldson, A.N.A., Villarroel, R., Parmar, M.K.B., Ernst, E. and Higginson, I.J., 2002. Efficacy of acupuncture in asthma: systematic review and meta-analysis of published data from 11 randomised controlled trials. European Respiratory Journal20(4), pp.846-852.

McCarney RW et al. Acupuncture for chronic asthma. Cochrane Database of Systematic Reviews 2003, Issue 3. Art. No.: CD000008. DOI: 10.1002/14651858.CD000008.pub2

Reinhold, T., Brinkhaus, B., Willich, S.N. and Witt, C., 2014. Acupuncture in patients suffering from allergic asthma: is it worth additional costs?. The Journal of Alternative and Complementary Medicine20(3), pp.169-177.

Helen
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